anti- Angiotensinogen antibody

Embark on a journey into the intricate world of blood pressure regulation and renal function with our Anti-Angiotensinogen Antibody, now available in a 100µg size. Angiotensinogen, a critical component of the renin-angiotensin system, is central to research exploring hypertension and kidney-related disorders.

Our Anti-Angiotensinogen Antibody is rigorously designed to provide exceptional specificity and sensitivity, making it suitable for various research applications, from ELISA to immunohistochemistry. Thorough validation ensures consistent and reproducible results, effectively reducing experimental variability and optimizing resource utilization.

With 100µg of high-quality antibody, this product offers sufficient material for multiple experiments, maintaining cost-effectiveness while ensuring research reliability. Engineered for user-friendliness, it accommodates researchers of all experience levels, enhancing the accuracy and dependability of experiments across diverse laboratory techniques.

Contribute to a deeper understanding of blood pressure regulation, renal function, and related fields with confidence, supported by our high-quality Anti-Angiotensinogen Antibody. Drive advancements in nephrology research and be part of groundbreaking discoveries in hypertension management.

Product Name

Angiotensinogen antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2b

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Angiotensinogen is a precursor of angiotensin II(Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme(ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

IMMUNOGEN INFORMATION

Immunogen

angiotensinogen(serpin peptidase inhibitor, clade A, member 8)

Synonyms

AGT, Ang I Angiotensin 2, Ang II Angiotensin 3, Ang III, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, ANHU, Des Asp[1] angiotensin II, FLJ92595, FLJ97926, Serpin A8, SERPINA8

Observed MW

53 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P01019

IMAGES