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SKU:FNab00455

anti- AP1,JUN,P39 antibody

anti- AP1,JUN,P39 antibody

Regular price $290.00 USD
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Introducing our Anti-AP1/JUN/P39 Antibody, a versatile and powerful tool meticulously designed to facilitate your research across a spectrum of cellular processes. This antibody, available in a 100µg size, provides a unique opportunity to investigate multiple critical proteins: AP1 (Adaptor Protein 1), JUN (a transcription factor), and P39 (a key regulator), all in one comprehensive package.

AP1 is a fundamental component of the adaptor protein complex, orchestrating intracellular cargo transport. JUN, a transcription factor, plays pivotal roles in gene regulation, while P39, also known as CDC2, is a vital cell cycle regulator. The combined recognition of these three proteins in one antibody offers exceptional specificity and sensitivity, ensuring precision and reliability for your research endeavors.

With 100µg of this high-quality antibody at your disposal, you have the flexibility to conduct a wide range of experiments. Whether you are exploring the interactions and roles of AP1, unraveling the transcriptional activities of JUN, or dissecting the cell cycle regulation governed by P39, this antibody empowers you with the precision required for impactful scientific discoveries.

Our Anti-AP1/JUN/P39 Antibody has undergone rigorous validation to ensure its reliability and reproducibility. You can trust in the consistency of your results, enabling you to draw accurate conclusions and make significant strides in your research endeavors, spanning cellular transport, gene regulation, and cell cycle control.

The recognition of these three critical proteins in one antibody simplifies experimental design and saves valuable resources. Whether you are an experienced researcher or new to these fields, our Anti-AP1/JUN/P39 Antibody promises to be an invaluable asset in your laboratory. Trust in its quality to drive your scientific discoveries forward, one experiment at a time, as you unravel the complexities of these essential cellular processes.

Product Name

AP1,JUN,P39 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer(CRC) cells(PubMed:24623306). Binds to the USP28 promoter in colorectal cancer(CRC) cells(PubMed:24623306).

IMMUNOGEN INFORMATION

Immunogen

jun oncogene

Synonyms

Activator protein 1, AP 1, AP1, c Jun, JUN, jun oncogene, P39, Proto oncogene c Jun, Transcription factor AP 1

Observed MW

40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P05412

IMAGES

 

Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using FNab00455(AP1,JUN,P39 Antibody) at dilution of 1:50
Immunofluorescent analysis of ( 4% PFA ) fixed HEK-293 cells using FNab00455 (AP1,JUN,P39 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00455(AP1,JUN,P39 Antibody) at dilution of 1:1000

 

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