anti- APAF1 antibody

Introducing our Anti-APAF1 Antibody, a crucial tool meticulously designed to empower your research in the intricate realm of apoptosis, the process of programmed cell death. APAF1, or Apoptotic Peptidase Activating Factor 1, is a central component of the apoptosome, a multi-protein complex responsible for initiating the caspase cascade and orchestrating apoptosis. Our carefully crafted antibody, available in a 100µg size, offers exceptional specificity and sensitivity, ensuring the precision and reliability essential for your research endeavors.

With 100µg of this high-quality antibody at your disposal, you have the flexibility to conduct a wide range of experiments and assays. Whether you're investigating APAF1's roles in apoptotic signaling pathways, exploring its interactions with other apoptotic regulators, or dissecting its implications in cancer, neurodegenerative diseases, or tissue development, this antibody empowers you with the precision required for impactful scientific discoveries.

Our Anti-APAF1 Antibody has undergone rigorous validation to ensure its reliability and reproducibility. You can trust in the consistency of your results, enabling you to draw accurate conclusions and make significant strides in your research endeavors, particularly in the fields of cell biology, cancer research, and apoptosis-related diseases.

APAF1's pivotal functions in regulating programmed cell death demand an antibody of exceptional quality, and our product is precisely engineered to meet these demands. Whether you are an experienced cell biologist, cancer researcher, or just beginning your scientific journey, our Anti-APAF1 Antibody promises to be an invaluable asset in your laboratory. Trust in its quality to drive your scientific discoveries forward, one experiment at a time, as you delve deeper into the complexities of apoptosis and its implications in health and disease.

Product Name

APAF1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9(Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

IMMUNOGEN INFORMATION

Immunogen

apoptotic peptidase activating factor 1

Synonyms

APAF 1, APAF1, CED4, KIAA0413

Observed MW

140 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP, IF

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O14727

IMAGES