FineTest
SKU:FNab00479
anti- APEX1 antibody
anti- APEX1 antibody
Couldn't load pickup availability
Uncover the mysteries of DNA repair and oxidative stress response with our Anti-APEX1 Antibody. APEX1, or Apurinic/Apyrimidinic Endodeoxyribonuclease 1, is a key enzyme essential for DNA base excision repair and redox regulation. Our meticulously crafted antibody, available in a 100µg size, provides exceptional specificity and sensitivity, ensuring the precision and reliability required for your research endeavors.
With 100µg of this high-quality antibody at your disposal, you have the flexibility to conduct a wide range of experiments. Whether you're exploring APEX1's roles in DNA damage repair, deciphering its interactions within DNA repair complexes, or delving into its implications in cancer and aging, this antibody empowers you with the precision needed for impactful scientific discoveries.
Our Anti-APEX1 Antibody has undergone rigorous validation to ensure its reliability and reproducibility. Trust in the consistency of your results, enabling you to draw accurate conclusions and make significant strides in your research endeavors, particularly in the fields of genomics, cancer research, and DNA repair mechanisms.
Unleash the power of DNA repair and redox regulation with confidence. Whether you are an experienced molecular biologist or just beginning your scientific journey, our Anti-APEX1 Antibody promises to be an invaluable asset in your laboratory, driving your research forward as you explore the intricate world of DNA maintenance and cellular defense mechanisms.
-
Product Name
APEX1 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
BACKGROUND
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
IMMUNOGEN INFORMATION
Immunogen
APEX nuclease (multifunctional DNA repair enzyme) 1
Synonyms
APE, APE1, APEX, APX, HAP1, REF1
Observed MW
39 kDa
APPLICATION
Tested Application
ELISA, WB, IP, IF
Recommended Dilution
WB: 1:500 - 1:2000; IF: 1:50 - 1:100; IP: 1:50 - 1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
