anti- APH1A antibody

Unlock the mysteries of cellular signaling and Alzheimer's disease with our Anti-APH1A Antibody. APH1A, or Anterior Pharynx Defective 1 Homolog A, is a pivotal component of the γ-secretase complex, a molecular machine crucial for the processing of amyloid precursor protein and the generation of amyloid-beta peptides implicated in Alzheimer's disease. Our meticulously crafted antibody, available in a 100µg size, provides exceptional specificity and sensitivity, ensuring the precision and reliability required for your research endeavors.

With 100µg of this high-quality antibody at your disposal, you have the flexibility to conduct a wide range of experiments. Whether you're exploring APH1A's roles in amyloid-beta production, investigating its interactions within the γ-secretase complex, or diving into its implications in neurodegenerative diseases, this antibody empowers you with the precision needed for impactful scientific discoveries.

Our Anti-APH1A Antibody has undergone rigorous validation to ensure its reliability and reproducibility. Trust in the consistency of your results, enabling you to draw accurate conclusions and make significant strides in your research endeavors, particularly in the field of Alzheimer's disease and neurodegeneration.

Unlock the secrets of Alzheimer's disease and cellular signaling with confidence. Whether you are an experienced neuroscientist or just embarking on your scientific journey, our Anti-APH1A Antibody promises to be an invaluable asset in your laboratory, driving your research forward as you seek to unravel the complexities of this devastating disease.

Product Name

APH1A antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP(beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.

IMMUNOGEN INFORMATION

Immunogen

anterior pharynx defective 1 homolog A

Synonyms

APH 1A, Aph 1alpha, APH1A, CGI 78, Gamma secretase subunit APH 1A, PSF, UNQ579/PRO1141

Observed MW

30 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500 - 1:1000

UNIPROT INFORMATION

UniProt ID

Q96BI3

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