anti- APOBEC3G antibody

Unleash the power of precision research with our Anti-APOBEC3G Antibody, now available in a convenient 100µg size. APOBEC3G, a vital member of the APOBEC family of proteins, plays a pivotal role in innate immunity by restricting viral replication.

Our antibody is meticulously crafted for exceptional specificity and sensitivity, ensuring accurate and reproducible results in a range of applications, from Western blotting to immunoprecipitation. Whether you're investigating APOBEC3G's antiviral mechanisms or its implications in cancer, our antibody is your trusted research ally.

The 100µg size offers versatility for both small-scale experiments and larger research initiatives. Its consistent quality and purity make it an ideal choice for researchers across diverse disciplines, from virology to immunology.

Choose our Anti-APOBEC3G Antibody to accelerate your research and gain fresh insights into APOBEC3G-related processes. Rely on its performance and join the community of scientists who trust our products to drive scientific discovery.

Product Name

APOBEC3G antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

DNA deaminase(cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and-independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity also against simian immunodeficiency viruses(SIVs), hepatitis B virus(HBV), equine infectious anemia virus(EIAV), xenotropic MuLV-related virus(XMRV) and simian foamy virus(SFV). May inhibit the mobility of LTR and non-LTR retrotransposons.

IMMUNOGEN INFORMATION

Immunogen

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G

Synonyms

APOBEC related protein, APOBEC related protein 9, APOBEC3G, ARCD, ARP 9, ARP9, bK150C2.7, CEM 15, CEM15, MDS019

Observed MW

46 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9HC16

IMAGES