anti- APRT antibody

Unlock the secrets of purine metabolism and rare genetic diseases with our Anti-APRT Antibody, now available in a convenient 100µg size. Adenine Phosphoribosyltransferase (APRT) is a crucial enzyme involved in the salvage pathway of purine biosynthesis.

This antibody is expertly crafted for exceptional specificity and sensitivity, ensuring reliable and reproducible results in various applications, from Western blotting to immunohistochemistry. Whether you're exploring APRT's functions in gout or its implications in purine metabolism disorders, our antibody is your dependable research partner.

The 100µg size offers cost-effective versatility, accommodating both small-scale experiments and larger research projects. Its consistent quality and purity make it an ideal choice for researchers across diverse disciplines, from biochemistry to clinical genetics.

Choose our Anti-APRT Antibody to propel your research forward and gain deeper insights into APRT-related processes. Count on its performance and join the community of scientists who rely on our products to advance scientific understanding.

Product Name

APRT antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2, 8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

adenine phosphoribosyltransferase

Observed MW

21 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P07741

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