anti- ARHGEF5 antibody

Embark on a journey into the world of Rho guanine nucleotide exchange factors (ARHGEFs) with our Anti-ARHGEF5 Antibody, available in a convenient 100µg size. ARHGEF5, also known as TIM, is a key regulator of Rho family GTPases, playing a pivotal role in cytoskeletal dynamics, cell migration, and signaling pathways.

This highly specific antibody offers exceptional sensitivity and specificity, ensuring accurate and reproducible results in various applications, from Western blotting to immunofluorescence. Whether you're investigating ARHGEF5's functions in neuronal development, its role in cancer metastasis, or its implications in cardiovascular health, our antibody is your trusted research partner.

The 100µg size provides cost-effective versatility, accommodating both small-scale experiments and larger research projects. Its consistent quality and purity make it an ideal choice for researchers across diverse disciplines, from cell biology to neuroscience.

With our Anti-ARHGEF5 Antibody, you can advance your research and gain deeper insights into the complex world of Rho GTPase regulation. Count on its exceptional performance, reliability, and specificity to drive your scientific discovery forward.

Product Name

ARHGEF5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Guanine nucleotide exchange factor which activates Rho GTPases(PubMed:15601624). Strongly activates RHOA(PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1(By similarity). Involved in regulation of cell shape and actin cytoskeletal organization(PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia(PubMed:14662653). Required for SRC-induced podosome formation(By similarity). Involved in positive regulation of immature dendritic cell migration(By similarity).

IMMUNOGEN INFORMATION

Immunogen

Rho guanine nucleotide exchange factor(GEF) 5

Synonyms

TIM

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q12774

IMAGES