anti- ARL3 antibody

Explore the fascinating world of intracellular vesicle trafficking and ciliary transport with our Anti-ARL3 Antibody, available in a convenient 100µg size. ARL3, a member of the ADP-ribosylation factor-like protein family, is a crucial regulator of vesicle transport and ciliary function, influencing various cellular processes, including ciliary protein trafficking and organelle dynamics.

This highly specific antibody offers exceptional sensitivity and specificity, ensuring accurate and reproducible results in various applications, from Western blotting to immunofluorescence. Whether you're investigating ARL3's functions in ciliogenesis, its role in cellular homeostasis, or its implications in ciliopathies and developmental disorders, our antibody is your trusted research companion.

The 100µg size provides cost-effective versatility, accommodating both small-scale experiments and larger research initiatives. Its consistent quality and purity make it an ideal choice for researchers across diverse disciplines, from cell biology to genetics.

Choose our Anti-ARL3 Antibody to propel your research forward and gain fresh insights into the complex world of intracellular vesicle dynamics and ciliary biology. Rely on its performance, specificity, and reliability to drive your scientific discovery forward and contribute to the body of knowledge in your field.

Product Name

ARL3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins(GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.

IMMUNOGEN INFORMATION

Immunogen

ADP-ribosylation factor-like 3

Synonyms

ARFL3

Observed MW

20 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P36405

IMAGES