anti- ARNT2 antibody

Uncover the mysteries of neural development and cellular differentiation with our Anti-ARNT2 Antibody, available in a convenient 100µg size. ARNT2, a member of the ARNT family, plays a pivotal role in regulating gene expression and influencing various developmental processes, including neuronal differentiation and oxygen sensing.

This highly specific antibody offers exceptional sensitivity and specificity, ensuring accurate and reproducible results in various applications, from immunohistochemistry to chromatin immunoprecipitation. Whether you're exploring ARNT2's functions in neural stem cell fate determination, its role in neurodegenerative diseases, or its implications in oxygen sensing pathways, our antibody is your dependable research partner.

The 100µg size provides cost-effective versatility, accommodating both small-scale experiments and larger research projects. Its consistent quality and purity make it an ideal choice for researchers across diverse disciplines, from neurobiology to developmental biology.

Choose our Anti-ARNT2 Antibody to advance your research and gain deeper insights into the intricate world of neural development and cellular differentiation. Rely on its performance, specificity, and reliability to drive your scientific discovery forward and contribute to the body of knowledge in your field.

Product Name

ARNT2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

IMMUNOGEN INFORMATION

Immunogen

aryl-hydrocarbon receptor nuclear translocator 2

Synonyms

BHLHE1, KIAA0307

Observed MW

79 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9HBZ2

IMAGES