anti- ATF6B antibody

Embark on a journey to explore the functions of ATF6B with our Anti-ATF6B Antibody, now available in a convenient 100µg size. ATF6B, a transcription factor belonging to the ATF/CREB family, is involved in diverse cellular processes, including the unfolded protein response (UPR) and gene regulation.

Our meticulously developed monoclonal antibody ensures unparalleled specificity and sensitivity, making it the ideal choice for a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence. It provides the precision and reliability needed for accurate results in your research.

With 100µg at your disposal, you have an ample supply for multiple experiments, reducing interruptions and allowing you to maintain the momentum of your research.

Don't miss the opportunity to shed light on the multifaceted functions of ATF6B. With our Anti-ATF6B Antibody, you can confidently delve into your research and uncover the secrets hidden within this intriguing transcription factor.

Product Name

ATF6B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resulting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody could recognize ATF6 beta (110kd) and its cleaved forms(60,80kd )(PMID: 11256944)

IMMUNOGEN INFORMATION

Immunogen

activating transcription factor 6 beta

Synonyms

CREBL1, G13

Observed MW

110 kDa, 60 kDa, 80 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:1000-1:4000; IP:1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q99941

IMAGES