anti- ATG4C antibody

Navigate the complex role of ATG4C in autophagy with our Anti-ATG4C Antibody, available in a 100µg size. ATG4C, a critical autophagy-related protein, is involved in the processing and maturation of autophagosomes, crucial for cellular quality control and the removal of damaged components.

Our meticulously developed monoclonal antibody ensures unparalleled specificity and sensitivity, making it the ideal choice for a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence. It provides the precision and reliability needed for accurate results in your autophagy research.

With 100µg at your disposal, you have an ample supply for multiple experiments, minimizing interruptions and allowing you to maintain the momentum of your research.

Don't miss the opportunity to shed light on the multifaceted functions of ATG4C in autophagy. With our Anti-ATG4C Antibody, you can confidently delve into your research and uncover the secrets hidden within this essential autophagy-related protein.

Product Name

ATG4C antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation(By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

IMMUNOGEN INFORMATION

Immunogen

ATG4 autophagy related 4 homolog C

Synonyms

APG4C, AUTL1, AUTL3

Observed MW

52-55 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q96DT6

IMAGES