anti- ATG7 antibody

Decipher the role of ATG7 in autophagy with our Anti-ATG7 Antibody, available in a 100µg size. ATG7, a critical autophagy-related protein, plays a pivotal role in autophagosome formation and the conjugation of critical proteins essential for cellular quality control and recycling.

Our meticulously developed monoclonal antibody ensures unparalleled specificity and sensitivity, making it the ideal choice for a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence. It provides the precision and reliability needed for accurate results in your autophagy research.

With 100µg at your disposal, you have an ample supply for multiple experiments, minimizing interruptions and allowing you to maintain the momentum of your research.

Don't miss the opportunity to shed light on the multifaceted functions of ATG7 in autophagy. With our Anti-ATG7 Antibody, you can confidently delve into your research and uncover the secrets hidden within this essential autophagy-related protein.

Product Name

ATG7 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport(Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation.

IMMUNOGEN INFORMATION

Immunogen

ATG7 autophagy related 7 homolog

Synonyms

APG7L

APPLICATION

Tested Application

ELISA

UNIPROT INFORMATION

UniProt ID

O95352