FineTest
SKU:FNab00728
anti- ATP8A1 antibody
anti- ATP8A1 antibody
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Delve into the intricate world of cellular phospholipid flipping with our Anti-ATP8A1 Antibody. This 100µg antibody is your key to uncovering the role of ATP8A1, a vital component in membrane asymmetry.
Designed for precision and reliability, this antibody excels in a range of applications, from Western blotting to immunohistochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results.
ATP8A1 plays a pivotal role in maintaining membrane integrity and phospholipid asymmetry, making it a central component of cellular homeostasis. With this antibody in your toolkit, you're better equipped to explore its functions. Whether you're investigating membrane repair mechanisms or studying diseases related to ATP8A1, this antibody is your trusted ally.
Elevate your research to new heights by ordering your Anti-ATP8A1 Antibody today and gain deeper insights into the complex world of cellular phospholipid dynamics.
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Product Name
ATP8A1 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine(PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine(PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.
IMMUNOGEN INFORMATION
Immunogen
ATPase, aminophospholipid transporter(APLT), class I, type 8A, member 1
Synonyms
ATP8A1, ATPase II, ATPASEII, ATPIA, ATPP2, Chromaffin granule ATPase II
Observed MW
120kd
APPLICATION
Tested Application
ELISA, WB
Recommended Dilution
WB: 1:500-1:2000
UNIPROT INFORMATION
UniProt ID
IMAGES
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00728(ATP8A1 antibody) at dilution of 1:1000
