anti- Autotaxin antibody

Navigate the intricate pathways of lysophospholipid signaling with our Anti-Autotaxin Antibody (Polyclonal). This 100µg antibody is your passport to uncovering the role of autotaxin, a critical enzyme in lysophospholipid metabolism.

Engineered for precision and reliability, this polyclonal antibody excels in a range of applications, from Western blotting to immunohistochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, empowering you to advance your research with confidence.

Autotaxin plays a pivotal role in lysophosphatidic acid production, making it an essential component of signaling pathways involved in inflammation, cancer, and more. With this polyclonal antibody in your toolkit, you're better equipped to explore its functions. Whether you're investigating immune responses or studying diseases related to lysophospholipid signaling, this antibody is your trusted research companion.

Elevate your research to new heights by ordering your Anti-Autotaxin Antibody (Polyclonal) today and gain deeper insights into the complex world of lysophospholipid biology.


Product Name

Autotaxin antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Hydrolyzes lysophospholipids to produce lysophosphatidic acid(LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.

IMMUNOGEN INFORMATION

Immunogen

ectonucleotide pyrophosphatase/phosphodiesterase 2

Synonyms

ATX, ATX X, Autotaxin, E NPP 2, ENPP2, FLJ26803, LysoPLD, PD IALPHA, PDNP2

Observed MW

100kd

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q13822

IMAGES