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FNab00781

anti- BACE1 antibody

anti- BACE1 antibody

$310.00 USD
$310.00 USD
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Conduct comprehensive BACE1 exploration with our Anti-BACE1 Antibody. This 100µg polyclonal antibody is your key to unraveling the multifaceted roles of BACE1, an enzyme involved in the cleavage of amyloid precursor protein (APP) and its implications in Alzheimer's disease.

Engineered for precision and reliability, this antibody excels in a range of applications, from Western blotting to immunohistochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, allowing you to advance your research with confidence.

BACE1 is a central focus in Alzheimer's disease research, where its inhibition is a promising therapeutic avenue. With this polyclonal antibody in your arsenal, you're better equipped to explore BACE1 functions comprehensively. Whether you're investigating amyloid-beta generation or studying potential drug targets, this antibody is your trusted research partner.

Invest in scientific excellence by ordering your Anti-BACE1 Polyclonal Antibody today and embark on a journey towards a deeper understanding of BACE1 biology.

Product Name

BACE1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

IMMUNOGEN INFORMATION

Immunogen

beta-site APP-cleaving enzyme 1

Synonyms

BACE, KIAA1149

Observed MW

70-75 kDa

APPLICATION

Tested Application

ELISA, WB, IP, IHC

Recommended Dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:100-1:400

UNIPROT INFORMATION

UniProt ID

P56817

IMAGES

 

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab00781(BACE1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
IP Result of anti-BACE1 (IP:FNab00781, 3ug; Detection:FNab00781 1:500) with mouse brain tissue lysate 5000ug.
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00781(BACE1 antibody) at dilution of 1:500

 

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