anti- BAK antibody

Dive into the world of apoptosis research with our Anti-BAK Antibody. This 100µg antibody is your gateway to uncovering the pivotal role of BAK, a key protein involved in programmed cell death.

Engineered for precision and reliability, this antibody excels in a range of applications, from Western blotting to immunohistochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, allowing you to advance your research with confidence.

BAK is known for its central role in the regulation of apoptosis, making it a crucial target in cancer research and drug development. With this antibody in your arsenal, you're better equipped to explore the functions of BAK. Whether you're investigating anti-cancer therapies or studying apoptosis signaling pathways, this antibody is your trusted research companion.

Elevate your scientific endeavors by ordering your Anti-BAK Antibody today and gain deeper insights into the intricate world of BAK-mediated apoptosis.

Product Name

BAK antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

IMMUNOGEN INFORMATION

Immunogen

BCL2-antagonist/killer 1

Synonyms

Apoptosis regulator BAK, BAK, BAK LIKE, BAK1, CDN1

Observed MW

26 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

Q16611

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