anti- BARD1 antibody

Uncover the roles of BARD1 with our Anti-BARD1 Antibody. This 100µg antibody is your passport to deciphering the functions of BARD1, a protein involved in DNA repair and genome stability.

Engineered for precision and reliability, this antibody excels in a range of applications, from Western blotting to immunohistochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, allowing you to advance your research with confidence.

BARD1 is a critical player in cellular responses to DNA damage and has implications in cancer research and therapy. With this antibody in your arsenal, you're better equipped to explore its functions. Whether you're investigating DNA repair mechanisms or studying cancer susceptibility, this antibody is your trusted research companion.

Elevate your scientific endeavors by ordering your Anti-BARD1 Antibody today and gain deeper insights into the dynamic world of BARD1 biology.

Product Name

BARD1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.

IMMUNOGEN INFORMATION

Immunogen

BRCA1 associated RING domain 1

Synonyms

BARD 1, BARD1, BRCA1 associated RING domain 1

Observed MW

90-100 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:1000

UNIPROT INFORMATION

UniProt ID

Q99728

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