anti- BAX antibody

Dive into the world of apoptosis research with our Anti-BAX Antibody. This 100µg antibody is your gateway to uncovering the pivotal role of BAX, a key protein involved in programmed cell death.

Engineered for precision and reliability, this antibody excels in a range of applications, from Western blotting to immunohistochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, allowing you to advance your research with confidence.

BAX is known for its central role in the regulation of apoptosis, making it a crucial target in cancer research and drug development. With this antibody in your arsenal, you're better equipped to explore the functions of BAX. Whether you're investigating anti-cancer therapies or studying apoptosis signaling pathways, this antibody is your trusted research companion.

Elevate your scientific endeavors by ordering your Anti-BAX Antibody today and gain deeper insights into the intricate world of BAX-mediated apoptosis.

Product Name

BAX antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

IMMUNOGEN INFORMATION

Immunogen

BCL2-associated X protein

Synonyms

BCL2L4, Apoptosis regulator BAX, BAX

Observed MW

21 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q07812

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