FineTest
SKU:FNab00810
anti- BAX antibody
anti- BAX antibody
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Dive into the world of apoptosis research with our Anti-BAX Antibody. This 100µg antibody is your gateway to uncovering the pivotal role of BAX, a key protein involved in programmed cell death.
Engineered for precision and reliability, this antibody excels in a range of applications, from Western blotting to immunohistochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, allowing you to advance your research with confidence.
BAX is known for its central role in the regulation of apoptosis, making it a crucial target in cancer research and drug development. With this antibody in your arsenal, you're better equipped to explore the functions of BAX. Whether you're investigating anti-cancer therapies or studying apoptosis signaling pathways, this antibody is your trusted research companion.
Elevate your scientific endeavors by ordering your Anti-BAX Antibody today and gain deeper insights into the intricate world of BAX-mediated apoptosis.
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Product Name
BAX antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction(PMID: 9108035). BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria(PMID: 21763611). The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis(PMID: 8183579).
IMMUNOGEN INFORMATION
Immunogen
BCL2-associated X protein
Synonyms
BCL2L4,Apoptosis regulator BAX, BAX
Observed MW
21 kDa
APPLICATION
Tested Application
ELISA, WB, IHC, IP, FC
Recommended Dilution
WB: 1:1000-1:10000; IP: 1:1000-1:10000; IHC: 1:20-1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
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Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab00810(BAX Antibody) at dilution of 1:50 -
IP Result of anti-BAX (IP: FNab00810, 3ug; Detection: FNab00810 1:2000) with Raji cells lysate 3500ug. -
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00810(BAX antibody) at dilution of 1:1000
