anti- BCCIP antibody

Investigate the functions of BCCIP with our Anti-BCCIP Antibody. This 100µg antibody is your passport to exploring the roles of BCCIP, a protein involved in DNA repair and cell cycle regulation.

Engineered for precision and reliability, this antibody excels in various applications, from immunoprecipitation to immunofluorescence. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, making it an invaluable tool in your research.

BCCIP, also known as BRCA2 and CDKN1A-interacting protein, is crucial for maintaining genomic integrity and has implications in cancer research. With this antibody in your arsenal, you're better equipped to investigate its functions. Whether you're studying DNA repair mechanisms or its role in tumor suppression, this antibody is your trusted research companion.

Elevate your scientific endeavors by ordering your Anti-BCCIP Antibody today and gain deeper insights into the intricate world of BCCIP biology.

Product Name

BCCIP antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.

IMMUNOGEN INFORMATION

Immunogen

BRCA2 and CDKN1A interacting protein

Synonyms

TOK1

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9P287

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