anti- BCL2 antibody

Probe the intricacies of BCL2 in apoptosis regulation with our Anti-BCL2 Antibody. This 100µg antibody is your key to unraveling the roles of BCL2, a critical protein involved in the control of programmed cell death.

Engineered for accuracy and reliability, this antibody excels in various applications, from Western blotting to immunofluorescence. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, allowing you to advance your research with confidence.

BCL2, a proto-oncogene, is central to the apoptotic pathway and has implications in cancer research and therapeutic development. With this antibody in your toolkit, you're better equipped to investigate its functions. Whether you're studying cell survival or its role in cancer progression, this antibody is your trusted research partner.

Elevate your scientific endeavors by ordering your Anti-BCL2 Antibody today and gain deeper insights into the dynamic world of BCL2 biology.

Product Name

BCL2 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785).

IMMUNOGEN INFORMATION

Immunogen

B-cell CLL/lymphoma 2

Synonyms

Apoptosis regulator Bcl 2, B cell CLL/lymphoma 2, BCL2, Oncogene B cell leukemia 2

Observed MW

26 kDa

APPLICATION

Tested Application

ELISA, WB, IP, IHC

Recommended Dilution

WB: 1:1000-1:10000; IP: 1:500-1:5000; IHC: 1:100-1:2000

UNIPROT INFORMATION

UniProt ID

P10415

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