anti- BCR antibody

Unveil the functions of BCR in cellular signaling with our Anti-BCR Antibody. This 100µg antibody is your key to exploring the roles of BCR, a critical protein involved in B-cell receptor signaling and immune responses.

Engineered for accuracy and reliability, this antibody excels in various applications, from immunoprecipitation to immunofluorescence. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, making it an indispensable tool in your research.

BCR, also known as B-cell receptor, plays a pivotal role in B-cell activation and has implications in immune-related disorders. With this antibody in your toolkit, you're better equipped to investigate its functions. Whether you're studying immune signaling or its role in autoimmune diseases, this antibody is your trusted research partner.

Elevate your scientific endeavors by ordering your Anti-BCR Antibody today and gain deeper insights into the intricate world of BCR biology.

Product Name

BCR antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

breakpoint cluster region

Synonyms

BCR1, D22S11

Observed MW

150 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P11274

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