anti- Beclin 1 antibody

Navigate the intricate pathways of autophagy with our Anti-Beclin 1 Antibody. This 100µg antibody is your guiding star to explore the functions of Beclin 1, a critical protein in autophagic processes.

Engineered for precision and reliability, this antibody excels in various applications, from immunoprecipitation to immunocytochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, making it an indispensable tool in your autophagy research.

Beclin 1, a key autophagy regulator, plays a pivotal role in cellular homeostasis and has implications in various diseases. With this antibody in your arsenal, you're better equipped to investigate its functions. Whether you're studying its role in cellular stress responses or its involvement in cancer, this antibody is your trusted research companion.

Illuminate the path to scientific discovery by ordering your Anti-Beclin 1 Antibody today and gain deeper insights into the dynamic world of autophagy and cell survival.

Product Name

Beclin 1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Beclin-1(BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.

IMMUNOGEN INFORMATION

Immunogen

beclin 1, autophagy related

Synonyms

ATG6, Beclin 1, beclin 1, autophagy related, beclin1, BECN1, GT197, Protein GT197, VPS30

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, IHC, WB,IF

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q14457

IMAGES