anti- BID antibody

Uncover the secrets of the apoptotic pathway with our Anti-BID Antibody. This 100µg antibody is your indispensable tool for investigating BID (BH3-interacting domain death agonist), a critical proapoptotic protein that plays a pivotal role in programmed cell death.

Designed with precision and reliability in mind, this antibody exhibits exceptional specificity and sensitivity, ensuring the accuracy of your results in various applications, including western blotting, immunoprecipitation, and immunohistochemistry.

BID serves as a central player in apoptosis, where it bridges the extrinsic and intrinsic apoptotic pathways. Upon activation and cleavage, BID triggers the release of cytochrome c, initiating a cascade of events that leads to cell death. Understanding BID's regulation and function is essential for unraveling its implications in various biological processes and diseases.

Whether you are exploring cancer biology, neurodegenerative disorders, or cellular homeostasis, our Anti-BID Antibody empowers you to delve deep into the apoptotic pathway, potentially paving the way for novel therapeutic interventions and insights into cell death mechanisms.

Product Name

BID antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The major proteolytic product p15 BID allows the release of cytochrome c(By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.

IMMUNOGEN INFORMATION

Immunogen

BH3 interacting domain death agonist

Synonyms

BID, FP497, p11 BID, p22 BID

Observed MW

22 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P55957

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