anti- BID antibody

Delve into the intricate world of programmed cell death with our Anti-BID Antibody. This 100µg antibody is your key to investigating BID (BH3-interacting domain death agonist), a proapoptotic protein involved in the intrinsic apoptotic pathway.

Designed for precision and reliability, this antibody offers exceptional specificity and sensitivity, ensuring accurate results in a variety of applications, including western blotting, immunoprecipitation, and immunohistochemistry. Whether you're unraveling the mechanisms of apoptosis, studying cancer biology, or exploring neurodegenerative diseases, this antibody is an essential tool for your research.

BID is a pivotal player in apoptosis, where it acts as a bridge between the extrinsic and intrinsic apoptotic pathways. Its activation and cleavage trigger the release of cytochrome c, initiating the cascade of events leading to cell death. Understanding BID's regulation and function is essential for uncovering its implications in health and disease.

With our Anti-BID Antibody, you can shed light on the intricate mechanisms governing programmed cell death, potentially contributing to advancements in cancer therapy and treatments for neurodegenerative disorders.

Product Name

BID antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The major proteolytic product p15 BID allows the release of cytochrome c(By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.

IMMUNOGEN INFORMATION

Immunogen

BH3 interacting domain death agonist

Synonyms

BID, FP497, p11 BID, p22 BID

Observed MW

22 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:2000-1:10000

UNIPROT INFORMATION

UniProt ID

P55957

IMAGES