anti- BIN1 antibody

Explore the intricate world of cellular membrane dynamics with our Anti-BIN1 Antibody. This 100µg antibody is your gateway to investigating BIN1 (Bridging Integrator 1), a multifunctional protein that plays a crucial role in membrane remodeling, endocytosis, and vesicle trafficking.

This antibody is designed to offer both precision and reliability in your research endeavors, ensuring that you can effectively probe BIN1's functions. It is compatible with various experimental techniques, including immunofluorescence, western blotting, and immunoprecipitation, allowing you to gain insights into BIN1's involvement in cellular processes from multiple angles.

BIN1's diverse functions extend to its role as a tumor suppressor and regulator of muscle function. With this antibody, you can delve deep into understanding how BIN1 contributes to these processes, potentially uncovering novel therapeutic targets.

Unlock the mysteries of membrane dynamics and cellular regulation with our Anti-BIN1 Antibody – a vital tool for researchers in cell biology, cancer biology, and beyond.

Product Name

BIN1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

IMMUNOGEN INFORMATION

Immunogen

bridging integrator 1

Synonyms

AMPHL

Observed MW

65 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50

UNIPROT INFORMATION

UniProt ID

O00499

IMAGES