anti- BLMH antibody

Explore the functions of BLMH in methionine metabolism with our Anti-BLMH Antibody, available in a 100µg size. This antibody is your key to understanding the roles and mechanisms of BLMH, a critical enzyme involved in the degradation of methionine and homocysteine.

Engineered for precision and reliability, this antibody offers exceptional specificity and sensitivity, ensuring accurate results in applications such as western blotting, immunohistochemistry, and enzyme assays. Whether you're investigating BLMH's involvement in homocysteine metabolism, methionine salvage pathways, or its potential implications in cardiovascular health, this antibody enhances your research capabilities.

BLMH, also known as bleomycin hydrolase, plays a pivotal role in maintaining methionine homeostasis by participating in the catabolism of homocysteine, a process critical for transsulfuration and the synthesis of essential molecules like glutathione.

With our Anti-BLMH Antibody, you can explore BLMH's functions, contribute to the understanding of methionine metabolism, and potentially advance research in metabolic disorders and cardiovascular diseases. Elevate your research in biochemistry and molecular biology with this precision antibody.

Product Name

BLMH antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

IMMUNOGEN INFORMATION

Immunogen

bleomycin hydrolase

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50

UNIPROT INFORMATION

UniProt ID

Q13867

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