anti- BMI1 antibody

Unlock the mysteries of BMI1 with our Anti-BMI1 Antibody, available in a 100µg size. This polyclonal antibody is specially designed to investigate the functions and mechanisms of BMI1, a key player in epigenetic regulation.

As a polyclonal antibody, it offers superior versatility, making it suitable for a wide range of applications, including western blotting, immunohistochemistry, and chromatin immunoprecipitation. Whether you're studying BMI1's roles in stem cell maintenance, cancer progression, or transcriptional regulation, this antibody empowers your research with precision and sensitivity.

BMI1, a member of the Polycomb Group (PcG) proteins, is well-known for its involvement in epigenetic silencing and chromatin modification. It plays a crucial role in maintaining stem cell pluripotency and regulating gene expression.

With our Anti-BMI1 Antibody, you can delve deeper into the functions of BMI1, contribute to the understanding of epigenetic control mechanisms, and potentially uncover new therapeutic targets for cancer and regenerative medicine. Elevate your research in epigenetics and molecular biology with this precision antibody.

Product Name

BMI1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

IMMUNOGEN INFORMATION

Immunogen

BMI1 polycomb ring finger oncogene

Synonyms

BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51

Observed MW

43-45 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

P35226

IMAGES