anti- BMP10 antibody

Explore the intricacies of BMP10 (Bone Morphogenetic Protein 10) signaling pathways with our Anti-BMP10 Antibody. This 100µg antibody is your indispensable tool for investigating BMP10's roles in cardiovascular development and homeostasis.

Meticulously designed for precision and reliability, this antibody offers exceptional specificity and sensitivity, ensuring precise results in various applications, including immunofluorescence, western blotting, and immunoprecipitation. Whether you're researching cardiac biology, angiogenesis, or vascular disorders, this antibody is a vital asset for your studies.

BMP10, a member of the BMP family, is a critical player in cardiovascular development and function. It regulates endothelial cell behavior and contributes to the maintenance of vascular integrity, making it a promising target for cardiovascular therapies.

With our Anti-BMP10 Antibody, you can uncover the intricacies of BMP10 signaling, potentially leading to insights into cardiac development and innovative approaches for cardiovascular disease treatments.

Product Name

BMP10 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

IMMUNOGEN INFORMATION

Immunogen

bone morphogenetic protein 10

Observed MW

48 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

O95393

IMAGES