anti- BMPR2 antibody

Illuminate the intricate signaling pathways involving BMPR2 with our Anti-BMPR2 Antibody, now available in a 100µg size. This antibody is your tool for unraveling the roles and mechanisms of BMPR2 (Bone Morphogenetic Protein Receptor Type 2) in various cellular processes.

Engineered for precision and reliability, this antibody offers exceptional specificity and sensitivity, ensuring accurate results in applications such as western blotting, immunohistochemistry, and flow cytometry. Whether you're studying BMPR2's involvement in embryogenesis, tissue regeneration, or pulmonary hypertension, this antibody enhances your research capabilities.

BMPR2, a member of the TGF-β receptor superfamily, is a transmembrane receptor known for its critical role in mediating the effects of bone morphogenetic proteins (BMPs). BMPR2 is essential for embryonic development and tissue homeostasis.

With our Anti-BMPR2 Antibody, you can shed light on BMPR2's signaling functions, contribute to the understanding of cellular responses to BMPs, and potentially advance research in regenerative medicine and cardiovascular diseases. Elevate your research in molecular biology and cell signaling with this precision antibody.

Product Name

BMPR2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

IMMUNOGEN INFORMATION

Immunogen

bone morphogenetic protein receptor, type II(serine/threonine kinase)

Synonyms

PPH1

Observed MW

120kd,97kd

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:1000

UNIPROT INFORMATION

UniProt ID

Q13873

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