anti- BRAF antibody

Study BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase) with our Anti-BRAF Antibody, available in a 100µg size. This high-quality antibody is your indispensable tool for investigating the roles and functions of BRAF in cell signaling, oncogenesis, and targeted therapy.

Engineered for precision and reliability, this antibody offers exceptional specificity and sensitivity, ensuring accurate results in applications such as western blotting, immunohistochemistry, and flow cytometry. Whether you're studying BRAF's involvement in the MAPK/ERK pathway, melanoma progression, or kinase inhibitors, this antibody empowers your research with accuracy and versatility.

BRAF is a serine/threonine kinase that plays a pivotal role in cell signaling, particularly in the RAS-RAF-MAPK/ERK pathway. Mutations in BRAF are frequently associated with various cancers, making it an important therapeutic target.

With our Anti-BRAF Antibody, you can study BRAF's functionality, investigate its downstream signaling cascades, and potentially advance research in cancer biology and precision medicine. Elevate your research in cell signaling pathways and targeted therapies with this precision antibody.

Product Name

BRAF antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

IMMUNOGEN INFORMATION

Immunogen

v-raf murine sarcoma viral oncogene homolog B1

Synonyms

BRAF1, RAFB1

Observed MW

98 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P15056

IMAGES