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SKU:FNab00960

anti- BRMS1 antibody

anti- BRMS1 antibody

Regular price $290.00 USD
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Explore the functions of BRMS1 (Breast Cancer Metastasis Suppressor 1) with our Anti-BRMS1 Antibody, available in a 100µg size. This high-quality antibody is your versatile tool for investigating BRMS1's roles in metastasis suppression, cancer progression, and tumor microenvironment.

Engineered for precision and reliability, this antibody ensures exceptional sensitivity in applications such as western blotting, immunofluorescence, and co-immunoprecipitation. Whether you're studying BRMS1's involvement in tumor cell adhesion, motility, or its interactions with metastasis-related proteins, this antibody enhances your research capabilities.

BRMS1 is a well-known metastasis suppressor protein that plays a crucial role in inhibiting cancer cell metastasis. Understanding BRMS1's functions and its mechanisms of action is fundamental in deciphering its contributions to cancer biology and metastasis regulation.

With our Anti-BRMS1 Antibody, you can delve into BRMS1's functionality, explore its protein partners, and potentially advance research in cancer metastasis and therapeutic interventions. Elevate your research in metastasis suppression and tumor microenvironment with this precision antibody.

Product Name

BRMS1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.

IMMUNOGEN INFORMATION

Immunogen

breast cancer metastasis suppressor 1

Observed MW

28 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9HCU9

IMAGES

 

MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab00960( BRMS1 Antibody) at dilution of 1:600
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