anti- BTK antibody

Uncover the intricate functions of BTK (Bruton's Tyrosine Kinase) with our Anti-BTK Antibody, available in a 100µg size. This high-quality antibody is your versatile tool for investigating BTK's roles in B-cell receptor signaling, immune response regulation, and cancer therapeutics.

Engineered for precision and reliability, this antibody ensures exceptional sensitivity in applications such as western blotting, flow cytometry, and immunoprecipitation. Whether you're studying BTK's involvement in antibody production, lymphocyte development, or its interactions with downstream signaling molecules, this antibody enhances your research capabilities.

BTK, a cytoplasmic tyrosine kinase, plays a crucial role in B-cell signaling pathways and has garnered attention as a target for immunomodulatory drugs in B-cell malignancies. Understanding BTK's functions and its signaling cascades is fundamental in deciphering its contributions to immune responses and disease pathogenesis.

With our Anti-BTK Antibody, you can precisely investigate BTK's functionality, explore its role in immune cell activation, and potentially advance research in immunotherapy and B-cell-related disorders. Elevate your research in immunology and cancer biology with this precision antibody.

Product Name

BTK antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

IMMUNOGEN INFORMATION

Immunogen

Bruton agammaglobulinemia tyrosine kinase

Synonyms

AGMX1, ATK, BPK

Observed MW

70-76 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

Q06187

IMAGES