anti- C4(alpha chain) antibody

Delve into the world of the complement component 4 alpha chain (C4 alpha chain) with our Anti-C4 (Alpha Chain) Antibody, now available in a 100µg vial. The C4 alpha chain is a pivotal component of the complement system, a cornerstone of immune responses. Understanding its structure and function is fundamental to unraveling immune-related disorders and therapeutic development.

Our meticulously developed and rigorously tested Anti-C4 (Alpha Chain) Antibody is designed for precise and sensitive detection of the C4 alpha chain. Whether you're studying its roles in complement activation, immune defense, or its implications in diseases, this antibody offers the accuracy required for reliable results.

This versatile antibody is optimized for various applications, including immunohistochemistry, Western blotting, and immunoprecipitation. With its robust performance, you can confidently investigate the C4 alpha chain in diverse experimental setups.

Each 100µg vial of this antibody empowers you to advance scientific knowledge, uncover the complexities of the complement system, and contribute to the development of therapies targeting immune-related disorders with confidence.

Product Name

C4(alpha chain) antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Complement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular wights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody can recognize C4 precursor, C4 alpha chain, C4b, and C4d.

IMMUNOGEN INFORMATION

Immunogen

complement component 4A(Rodgers blood group)

Observed MW

95 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:1000-1:6000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P0C0L4

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