anti- C4BPB antibody

Unlock the secrets of complement component 4 binding protein beta (C4BPB) with our Anti-C4BPB Antibody, now available in a 100µg vial. C4BPB is a key player in the regulation of the complement system, a critical component of immune responses. Understanding its functions and interactions is essential for unraveling immune-related disorders and developing targeted therapies.

Our meticulously developed and rigorously tested Anti-C4BPB Antibody ensures precise and sensitive detection of C4BPB. Whether you're exploring its roles in complement regulation or its implications in diseases, this antibody guarantees reliable results.

This versatile antibody is optimized for various applications, including immunohistochemistry, Western blotting, and immunoprecipitation. With its robust performance, you can confidently investigate C4BPB in diverse experimental setups.

Each 100µg vial of this antibody empowers you to advance scientific knowledge, uncover the complexities of complement regulation, and contribute to the development of therapies targeting immune-related disorders with confidence.

Product Name

C4BPB antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

complement component 4 binding protein, beta

Synonyms

C4b binding protein beta chain, C4BP, C4BPB

Observed MW

40-45 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P20851

IMAGES