anti- C5AR1 antibody

Dive into the realm of immune regulation with our Anti-C5AR1 Antibody, now available in a 100µg vial. The C5AR1 receptor, a critical component of the complement system, plays a pivotal role in immune responses, inflammation, and host defense. Understanding its functions and regulation is essential for unraveling immune-related disorders and developing targeted therapies.

Our meticulously developed and rigorously tested Anti-C5AR1 Antibody is designed to provide precise and sensitive detection of C5AR1. Whether you're exploring its roles in immune cell activation, chemotaxis, or its implications in diseases, this antibody ensures reliable results.

This versatile antibody is optimized for various applications, including immunohistochemistry, Western blotting, and immunoprecipitation. With its robust performance, you can confidently investigate C5AR1 in diverse experimental setups.

Each 100µg vial of this antibody empowers you to advance scientific knowledge, uncover the complexities of the complement system, and contribute to the development of therapies targeting immune-related disorders with confidence.

Product Name

C5AR1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a(PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events(PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production(PubMed:10636859, PubMed:15153520).

IMMUNOGEN INFORMATION

Immunogen

complement component 5a receptor 1

Synonyms

C5AR, C5R1

Observed MW

45-50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

P21730

IMAGES