anti- CAD antibody

Delve into the intricate functions of Carbamoyl-phosphate synthase [ammonia], mitochondrial (CAD) with our Anti-CAD Antibody, now available in a 100µg vial. CAD is a multifunctional enzyme essential for de novo pyrimidine biosynthesis, making it a promising target for cancer therapy and antiviral drug development.

Our meticulously developed and rigorously tested Anti-CAD Antibody empowers you to explore the functions and roles of CAD with precision and accuracy. Whether you're investigating its roles in nucleotide metabolism, drug discovery, or its implications in cancer and viral infections, this antibody provides the specificity and sensitivity necessary for reliable results.

This versatile antibody is optimized for various applications, including immunohistochemistry, Western blotting, and immunoprecipitation. With its robust performance, you can confidently investigate CAD in diverse experimental setups.

Each 100µg vial of this antibody offers value and flexibility, allowing you to advance scientific knowledge and contribute to our understanding of CAD's critical functions in cellular processes and disease pathways with confidence.

Product Name

CAD antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.

IMMUNOGEN INFORMATION

Immunogen

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

Observed MW

243 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P27708

IMAGES