anti- CAMKK2 antibody

CAMKK2, or Calcium/Calmodulin-Dependent Protein Kinase Kinase 2, is a key regulator of calcium-dependent signaling pathways and plays essential roles in cellular processes, including autophagy and metabolism. Our Anti-CAMKK2 Antibody, available in a 100µg vial, is your essential tool for investigating the functions of CAMKK2 in various cellular pathways.

CAMKK2 is involved in activating downstream kinases, such as AMPK, which modulate processes like autophagy and energy homeostasis. This highly specific antibody is meticulously developed and rigorously validated to ensure accurate and reproducible results in your research. It is suitable for a range of applications, including Western blotting, immunofluorescence, and immunoprecipitation.

By using our Anti-CAMKK2 Antibody, you gain the confidence to explore CAMKK2's roles in cellular metabolism, autophagy regulation, and its potential implications in diseases such as cancer and metabolic disorders. This versatile research tool empowers you to advance your understanding of CAMKK2 and its significance in cell biology.

With a 100µg vial, you have ample antibody for multiple experiments, ensuring cost-effectiveness and flexibility in your research endeavors. Uncover the mysteries of CAMKK2 and its impact on cellular function with precision and reliability using our high-quality antibody.

Product Name

CAMKK2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase(AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals(By similarity). Seems to be involved in hippocampal activation of CREB1(By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.

IMMUNOGEN INFORMATION

Immunogen

calcium/calmodulin-dependent protein kinase kinase 2, beta

Synonyms

CAMKKB, KIAA0787

Observed MW

55-60 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IHC

Recommended Dilution

WB: 1:500-1:2000; IF: 1:20-1:200; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q96RR4

IMAGES