anti- CAPNS1 antibody

CAPNS1, or Calpain Small Subunit 1, is a crucial component of the calpain protein complex, which plays a role in cellular processes such as proteolysis and cytoskeletal regulation. Our Anti-CAPNS1 Antibody, available in a 100µg vial, is your essential tool for investigating the functions of CAPNS1 in various cellular pathways.

CAPNS1 is involved in the regulation of calpain activity, which is essential for processes like cell migration, apoptosis, and cytoskeletal remodeling. This highly specific antibody is meticulously developed and rigorously validated to ensure accurate and reproducible results in your research. It is suitable for a range of applications, including Western blotting, immunofluorescence, and immunoprecipitation.

With our Anti-CAPNS1 Antibody, you can explore CAPNS1's roles in calpain-mediated proteolysis, cellular remodeling, and its potential implications in diseases related to calpain dysfunction. This versatile research tool empowers you to advance your understanding of CAPNS1 and its significance in cell biology.

The 100µg vial size provides ample antibody for multiple experiments, ensuring cost-effectiveness and flexibility in your research endeavors. Uncover the mysteries of CAPNS1 and its impact on cellular function with precision and reliability using our high-quality antibody.

Product Name

CAPNS1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

calpain, small subunit 1

Synonyms

CAPN4, CAPNS

Observed MW

28 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P04632

IMAGES