anti- CARD9 antibody

CARD9 is a critical component of the immune system, playing a key role in innate immunity and inflammatory responses. Our Anti-CARD9 Antibody, available in a 100µg vial, is a valuable tool for studying CARD9's functions in immune signaling pathways and its potential implications in various immunological processes.

CARD9 is essential for orchestrating immune responses against infections and maintaining immune system homeostasis. This highly specific antibody is meticulously developed and rigorously validated to ensure accurate and reproducible results in your research. It is compatible with various applications, including Western blotting, immunohistochemistry, and flow cytometry.

With our Anti-CARD9 Antibody, you can explore CARD9's roles in immune signaling, host defense, and its involvement in inflammatory diseases. This versatile research tool empowers you to advance your understanding of CARD9 and its significance in immunology.

The 100µg vial size provides an ample supply of antibody for multiple experiments, ensuring cost-effectiveness and flexibility in your research endeavors. Dive into the intricate world of CARD9 and its impact on immune responses with precision and reliability using our high-quality antibody.

Product Name

CARD9 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Adapter protein that plays a key role in innate immune response to a number of intracellular pathogens, such as C.albicans and L.monocytogenes. Is at the crossroads of ITAM-tyrosine kinase and the Toll-like receptors(TLR) and NOD2 signaling pathways. Probably controls various innate immune response pathways depending on the intracellular pathogen. In response to L.monocytogenes infection, acts by connecting NOD2 recognition of peptidoglycan to downstream activation of MAP kinases(MAPK) without activating NF-kappa-B. Also involved in activation of myeloid cells via classical ITAM-associated receptors and TLR: required for TLR-mediated activation of MAPK, while it is not required for TLR-induced activation of NF-kappa-B(By similarity). Controls CLEC7A(dectin-1)-mediated myeloid cell activation induced by the yeast cell wall component zymosan, leading to cytokine production and innate anti-fungal immunity: acts by regulating BCL10-MALT1-mediated NF-kappa-B activation pathway. Activates NF-kappa-B via BCL10. In response to the hyphal form of C.albicans, mediates CLEC6A(dectin-2)-induced I-kappa-B kinase ubiquitination, leading to NF-kappa-B activation via interaction with BCL10. In response to fungal infection, may be required for the development and subsequent differentiation of interleukin 17-producing T helper(TH-17) cells.

IMMUNOGEN INFORMATION

Immunogen

caspase recruitment domain family, member 9

Observed MW

50-59kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9H257

IMAGES