anti- Caspase 10 antibody

Unlock the mysteries of programmed cell death with our Anti-Caspase 10 Antibody, now available in a convenient 100µg size. Caspase 10 is a critical component of apoptosis, playing a pivotal role in regulating cell death pathways. This antibody has been meticulously crafted to provide you with the highest specificity and sensitivity, ensuring reliable and reproducible results for your research endeavors.

Caspase 10 is involved in both extrinsic and intrinsic apoptotic pathways, making it a compelling target for studying cellular responses to stress and disease. Our 100µg antibody vial ensures you have an ample supply for multiple experiments, promoting cost-effectiveness and consistency in your research.

This versatile antibody is suitable for various applications, including Western blotting, immunohistochemistry, and immunoprecipitation, offering you flexibility in your experimental approach. Explore the world of apoptosis and cell death regulation with confidence, knowing that you have a dependable tool in your hands.

Product Name

Caspase 10 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a protein which is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

IMMUNOGEN INFORMATION

Immunogen

caspase 10, apoptosis-related cysteine peptidase

Synonyms

ALPS2, Apoptotic protease Mch 4, CASP 10, CASP10, Caspase 10, Caspase 10/p23/17/p12, Caspase10, FLICE2, ICE like apoptotic protease 4, MCH4

Observed MW

59kd

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q92851

IMAGES