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FineTest

SKU:FNab01296

anti- Caspase 9 antibody

anti- Caspase 9 antibody

Regular price $290.00 USD
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Our Anti-Caspase 9 Antibody (100µg) is a crucial tool for researchers studying apoptosis and cell death signaling pathways. Caspase 9, a key initiator caspase, is essential for the initiation of the mitochondrial pathway of apoptosis. This antibody, targeting Caspase 9, ensures precise and reliable results in your experiments.

With 100µg of this antibody at your disposal, you'll have an abundant supply for multiple experiments, reducing the need for frequent reordering. Whether you're conducting Western blots, immunohistochemistry, or flow cytometry, this antibody consistently delivers high-quality performance.

The specificity and sensitivity of this antibody are guaranteed, thanks to advanced production techniques and rigorous quality control. Its reliability makes it an invaluable asset for projects aimed at deciphering the intricate mechanisms of apoptosis and cell death.

Advance your apoptosis research with confidence using our Anti-Caspase 9 Antibody. By utilizing this antibody, you contribute to the broader understanding of cell death pathways and their implications in biology and disease.

Product Name

cleaved Caspase 9 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.This antibody can recognize the pre- and cleaved- caspase 9.

IMMUNOGEN INFORMATION

Immunogen

caspase 9, apoptosis-related cysteine peptidase

Synonyms

APAF 3, APAF3, Apoptotic protease Mch 6, CASP 9, CASP9, Caspase 9, CASPASE 9c, Caspase9, Caspase-9, ICE LAP6, ICE like apoptotic protease 6, MCH6

Observed MW

17kDa/36kDa/46kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:200 - 1:200; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P55211

IMAGES

 

Immunohistochemistry of paraffin-embedded rat brain using FNab01296 at dilution of 1:100
Immunofluorescence analysis of ( -20℃ Ethanol ) fixed A549 cells using FNab01296.
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01296 at dilution of 1:300

 

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