anti- CASQ2 antibody

Our Anti-CASQ2 Antibody (100µg) is a valuable tool for researchers studying cardiac muscle physiology and the regulation of calcium ion homeostasis. CASQ2, also known as calsequestrin-2, is a calcium-binding protein found in the sarcoplasmic reticulum of cardiomyocytes. This antibody, targeting CASQ2, ensures precise and reliable results in your experiments.

With 100µg of this antibody per vial, you'll have an ample supply for multiple experiments, reducing the need for frequent reordering. Whether you're conducting Western blots, immunohistochemistry, or investigating the role of CASQ2 in cardiac diseases like catecholaminergic polymorphic ventricular tachycardia (CPVT), this antibody consistently delivers high-quality performance.

Researchers can trust the specificity and sensitivity of this antibody, which is produced using advanced techniques and high-quality materials. Its reliability makes it an invaluable asset for projects aimed at deciphering the role of CASQ2 in calcium handling and cardiac muscle function.

Empower your research on cardiac physiology and calcium regulation with confidence using our Anti-CASQ2 Antibody. By utilizing this antibody, you contribute to the broader understanding of calcium-dependent processes in the heart and their implications in cardiac diseases.

Product Name

CASQ2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.

IMMUNOGEN INFORMATION

Immunogen

calsequestrin 2(cardiac muscle)

Observed MW

55 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O14958

IMAGES