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FineTest

FNab01327

anti- CBS antibody

anti- CBS antibody

$290.00 USD
$290.00 USD
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Delve into the field of sulfur metabolism and homocysteine regulation with our Anti-CBS Antibody, available in a 100µg size. CBS, or cystathionine beta-synthase, is a pivotal enzyme in the transsulfuration pathway, playing a critical role in the conversion of homocysteine to cysteine. This antibody has been meticulously crafted to provide high specificity and sensitivity, making it an indispensable tool for your research endeavors.

CBS is not only essential for amino acid metabolism but is also implicated in various diseases, including homocystinuria and cardiovascular disorders. Whether you're conducting Western blotting, immunohistochemistry, or enzyme activity assays, this antibody offers reliable and consistent results, ensuring the success of your metabolic research.

With 100µg of antibody in each vial, you'll have an ample supply to support multiple experiments, promoting cost-effectiveness without compromising data quality. Embark on your journey into sulfur metabolism research with confidence using our Anti-CBS Antibody.

Product Name

CBS antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine(PubMed:23981774, PubMed:20506325, PubMed:23974653). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons(By similarity).

IMMUNOGEN INFORMATION

Immunogen

cystathionine-beta-synthase

Synonyms

Beta thionase, CBS, cystathionine beta synthase, HIP4, Serine sulfhydrase

Observed MW

61 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P35520

IMAGES

 

Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using FNab01327(CBS Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Immunofluorescent analysis of U2OS cells, using FNab01327(CBS Antibody) at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
IP Result of anti-CBS (IP:FNab01327, 3ug; Detection:FNab01327 1:500) with mouse kidney tissue lysate 4000ug.
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab01327(CBS antibody) at dilution of 1:500

 

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