anti- CBX3 antibody

Unravel the mysteries of chromatin structure and epigenetic regulation with our Anti-CBX3 Antibody, available in a 100µg size. CBX3, also known as Chromobox Protein Homolog 3 or HP1 Gamma, is a key component of heterochromatin, playing a critical role in gene silencing and chromatin compaction. This antibody is meticulously developed to offer exceptional specificity and sensitivity, making it an invaluable tool for your research endeavors.

CBX3's involvement in epigenetic regulation and heterochromatin formation has implications for diverse biological processes, including transcriptional repression and genome stability. Whether you're conducting chromatin immunoprecipitation (ChIP), immunofluorescence, or studying chromatin structure, this antibody provides reliable and consistent results, ensuring the success of your research.

With 100µg of antibody in each vial, you'll have an ample supply to support multiple experiments, promoting cost-effectiveness without compromising data quality. Dive into the world of chromatin biology and epigenetics research with confidence using our Anti-CBX3 Antibody.

Product Name

CBX3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

chromobox homolog 3 (HP1 gamma homolog, Drosophila)

Observed MW

23 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q13185

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