anti- CCDC22 antibody

Unlock the mysteries of cellular biology and centriole function with our Anti-CCDC22 Antibody, available in a 100µg size. CCDC22, also known as Coiled-Coil Domain Containing 22, is a critical player in various cellular processes, including centriole duplication and cell division. This antibody is meticulously developed to offer exceptional specificity and sensitivity, making it an invaluable tool for your research endeavors.

CCDC22's roles in centriole function and cell division have implications for multiple areas of research, including cancer biology and developmental biology. Whether you're conducting immunofluorescence, immunoprecipitation, or studying centriole biogenesis, this antibody provides reliable and consistent results, ensuring the success of your experiments.

With 100µg of antibody in each vial, you'll have an ample supply to support multiple experiments, promoting cost-effectiveness without compromising data quality. Delve into the world of cellular and molecular biology research with confidence using our Anti-CCDC22 Antibody.

Product Name

CCDC22 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via assocation with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10(PubMed:23563313). Plays a role in copper ion homeostasis. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes(PubMed:25355947).

IMMUNOGEN INFORMATION

Immunogen

coiled-coil domain containing 22

Synonyms

CXorf37

Observed MW

71 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

O60826

IMAGES