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FineTest

SKU:FNab01456

anti- CD3 delta antibody

anti- CD3 delta antibody

Regular price $310.00 USD
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Embark on a journey through T-cell research with our Anti-CD3 Delta Polyclonal Antibody, now available in a convenient 100µg size. CD3 Delta, a fundamental component of the T-cell receptor (TCR) complex, plays a crucial role in T-cell activation and immune responses.

Our meticulously developed polyclonal antibody, derived from rabbit hosts, offers exceptional sensitivity and versatility for various research applications. Whether you're delving into flow cytometry, Western blotting, or immunohistochemistry, this antibody's polyclonal nature allows recognition of multiple epitopes, enhancing its utility in diverse research contexts.

With 100µg at your disposal, you have a generous supply for multiple experiments, reducing the need for frequent reordering and ensuring the continuity of your research.

Explore the multifaceted functions of CD3 Delta in T-cell activation, immune response regulation, and its implications in autoimmune diseases and immunotherapies. Our Anti-CD3 Delta Polyclonal Antibody empowers you to confidently investigate CD3 Delta-related research, shedding light on crucial mechanisms of immune regulation and paving the way for advancements in immunology and targeted therapies.

Whether you're an experienced researcher or just beginning your journey into the fascinating world of CD3 Delta, our antibody provides the precision, reliability, and quantity you need to drive your investigations forward. Navigate the complexities of T-cell biology with this indispensable research tool.

Product Name

CD3 delta antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

IMMUNOGEN INFORMATION

Immunogen

CD3d molecule, delta (CD3-TCR complex)

Observed MW

19 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P04234

IMAGES

 

Immunohistochemistry of paraffin-embedded rat spleen using FNab01456( CD3D Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01456(CD3D antibody) at dilution of 1:1000

 

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