anti- CD3 epsilon antibody

Delve into the intricate world of immune signaling with our Anti-CD3 Epsilon Polyclonal Antibody, available in a convenient 100µg size. CD3 Epsilon, a subunit of the CD3 complex, is a crucial component of the T-cell receptor (TCR) complex, essential for T-cell activation and regulation of immune responses.

Our meticulously developed polyclonal antibody, derived from rabbit hosts, offers exceptional sensitivity and versatility for various research applications. Whether you're delving into flow cytometry, Western blotting, or immunohistochemistry, this antibody's polyclonal nature allows recognition of multiple epitopes, enhancing its utility in diverse research contexts.

With 100µg at your disposal, you have a generous supply for multiple experiments, reducing the need for frequent reordering and ensuring the continuity of your research.

Explore the multifaceted functions of CD3 Epsilon in T-cell activation, immune response regulation, and its implications in autoimmune diseases and immunotherapies. Our Anti-CD3 Epsilon Polyclonal Antibody empowers you to confidently investigate CD3 Epsilon-related research, shedding light on crucial mechanisms of immune regulation and paving the way for advancements in immunology and targeted therapies.

Whether you're an experienced researcher or just beginning your journey into the fascinating world of CD3 Epsilon, our antibody provides the precision, reliability, and quantity you need to drive your investigations forward. Unlock the secrets of CD3 Epsilon and its pivotal role in immune responses with this powerful research tool.

Product Name

CD3 epsilon antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

IMMUNOGEN INFORMATION

Immunogen

CD3e molecule, epsilon (CD3-TCR complex)

Synonyms

CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE

Observed MW

23 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P07766

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