anti- CD3 epsilon antibody

Uncover the secrets of T-cell biology with our Anti-CD3 Epsilon Antibody, available in a 100µg size. CD3 Epsilon is an integral component of the T-cell receptor (TCR) complex, playing a central role in T-cell activation and immune responses.

This antibody is your gateway to a wide range of research applications, from flow cytometry to Western blotting and immunohistochemistry. With its precision and sensitivity, it ensures accurate and reliable results in your CD3 Epsilon-related experiments.

With 100µg at your disposal, you have an ample supply for multiple experiments, reducing the need for frequent reordering and ensuring the continuity of your research.

Explore the intricate world of T-cell signaling, immune regulation, and the potential applications of CD3 Epsilon in immunotherapies and autoimmune disease research. Our Anti-CD3 Epsilon Antibody empowers you to confidently advance your investigations, contributing to breakthroughs in immunology and targeted therapies.

Whether you're a seasoned researcher or new to the field of T-cell biology, this antibody provides the precision, reliability, and quantity you need to propel your research forward. Unveil the mysteries of CD3 Epsilon and its critical role in immune responses with this essential research tool.

Product Name

CD3 epsilon antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule.

IMMUNOGEN INFORMATION

Immunogen

CD3e molecule, epsilon (CD3-TCR complex)

Synonyms

CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE

Observed MW

23 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, FC

Recommended Dilution

WB: 1:2000 - 1:20000; IHC: 1:1000 - 1:10000; IF: 1:50 - 500

UNIPROT INFORMATION

UniProt ID

P07766

IMAGES